It seems on game launch I cannot click on any buttons with my mouse nor can I use the enter key or arrow keys (I basically cannot do anything but sit on the main menu). I have tried running in compatibility mode, running as an administrator, alt-tabbing out of the game and back in, and uninstalling/reinstalling to the same hard drive as well as a different one. Will update if I attempt any other "fixes".
*EDIT*
It turns out this is something on my end as it is happening in two of the new games I have just bought, one being Ylands. Will update when I find a fix.